What is the most common extraintestinal manifestation (EIM) of Crohn disease?

Updated: Jul 26, 2019
  • Author: Leyla J Ghazi, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Answer

Hepatobiliary disease is among the most common EIMs of Crohn disease and its therapies. Abnormal serum aminotransferase levels are common during the course of Crohn disease in children. Most aminotransferase elevations are transient and appear to relate to medications or disease activity. Aminotransferase elevations that persist for longer than 6 months should be investigated because the likelihood of serious liver disease is increased.


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