When do ophthalmologic manifestations of Crohn disease occur?

Updated: Jul 26, 2019
  • Author: Leyla J Ghazi, MD; Chief Editor: Praveen K Roy, MD, AGAF  more...
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Ophthalmologic manifestations of Crohn disease (primarily episcleritis and anterior uveitis) most frequently occur when the disease is active. The rate of such manifestations is 0.5-5% in the adult population but is lower in children and adolescents.

The most common ocular manifestation is episcleritis, or inflammation of the vascular-rich episclera. Episcleritis should be suspected in patients who present with acute redness in one or both eyes, irritation, and burning. Uveitis is usually symptomatic, causing pain or decreased visual acuity. Treatment for these ocular EIMs is geared toward controlling the underlying bowel disease.

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