Which medications in the drug class Antiemetics are used in the treatment of Cholecystitis?

Updated: May 20, 2021
  • Author: Alan A Bloom, MD; Chief Editor: BS Anand, MD  more...
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Patients with cholecystitis frequently experience nausea and vomiting. Antiemetics can help make the patient more comfortable and can prevent fluid and electrolyte abnormalities.

Promethazine (Phenergan, Promethegan, Phenadoz)

Promethazine is used for symptomatic treatment of nausea in vestibular dysfunction. It is an antidopaminergic agent effective in treating emesis. It blocks postsynaptic mesolimbic dopaminergic receptors in the brain and reduces stimuli to the brainstem reticular system.

Prochlorperazine (Compazine)

Prochlorperazine may relieve nausea and vomiting by blocking the postsynaptic mesolimbic dopamine receptors through anticholinergic effects and depressing the reticular activating system. In addition to the antiemetic effects, it has the advantage of augmenting hypoxic ventilatory response, acting as a respiratory stimulant at high altitude.

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