What is the role of upper endoscopy in the diagnosis of celiac disease?

Updated: Oct 10, 2018
  • Author: Stephan U Goebel, MD; Chief Editor: BS Anand, MD  more...
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Answer

Upper endoscopy with at least 6 duodenal biopsies is considered the criterion standard to help establish a diagnosis of celiac disease. Serology and endoscopy should be considered, especially in patients presenting with classical symptoms, evidence of malabsorption, and endoscopic findings, including mucosal fold scalloping, reduced mucosal folds, and mosaic pattern.


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