What is the role of hematologic tests in the diagnosis of celiac disease (sprue)?

Updated: Nov 29, 2019
  • Author: Stephan U Goebel, MD; Chief Editor: BS Anand, MD  more...
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Anemia due to deficiency in iron, folate, and, rarely, vitamin B-12 might be present. A low serum iron level is common. A systematic review of 18 studies comprising 2,998 patients with iron-deficiency anemia found that the prevalence of biopsy-confirmed celiac disease in these patients was about 1 in 31. [28]

The prothrombin time (PT) might be prolonged and the international normalized ratio (INR) may be elevated because of malabsorption of vitamin K.

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