What is the global prevalence of celiac disease (sprue)?

Updated: Nov 29, 2019
  • Author: Stephan U Goebel, MD; Chief Editor: BS Anand, MD  more...
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A 2018 systematic review and meta-analysis noted that celiac disease is a global public health concern. [11] The overall prevalence of this condition is 1.4% on the basis of serologic findings and 0.7% on the basis of biopsy findings. [11, 8] However, specific national population-based prevalence studies are needed because the prevalence of celiac disease varies with factors such as sex, age, and location. [11]

Approximately 3 million people in Europe and another 3 million people in the United States are estimated to be affected by celiac disease. Celiac disease is prevalent in European countries with temperate climates. The highest prevalence of celiac disease is in Ireland and Finland and in places to which Europeans emigrated, notably North America and Australia. In these populations, celiac disease affects approximately 1 in 100 individuals. The incidence of celiac disease is increasing among certain populations in Africa (Saharawui population), Asia (India), [12, 13]  and the Middle East.

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