Which medications in the drug class Immunosuppressants are used in the treatment of Primary Biliary Cholangitis (Primary Biliary Cirrhosis)?

Updated: Nov 08, 2017
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Inhibit key factors that mediate immune reactions.

Methotrexate (Rheumatrex, Folex)

Results of various trials suggest improvement in biochemical and histologic findings after treatment.

Prednisolone (Delta-Cortef)

May improve symptoms, biochemical findings, and histologic findings. Great concern exists about corticosteroid-induced osteoporosis.

Cyclosporine (Sandimmune, Neoral)

Has some therapeutic potential.

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