What are diagnostic considerations for primary biliary cholangitis (PBC)?

Updated: Nov 08, 2017
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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The differential diagnosis of primary biliary cholangitis also includes idiopathic adulthood ductopenia.

It is important to note the following:

  • Middle-aged women with pruritus and jaundice must be screened for primary biliary cholangitis. Treatment with ursodeoxycholic acid (UDCA) must be started, and periodic follow-up care should be scheduled.
  • The level of hyperbilirubinemia and the Mayo risk score are of prognostic value.

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