What is the staging for primary biliary cholangitis (PBC)?

Updated: Nov 08, 2017
  • Author: Nikolaos T Pyrsopoulos, MD, PhD, MBA, FACP, AGAF; Chief Editor: BS Anand, MD  more...
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Answer

Staging

  • Stage 1 (portal stage of Ludwig): Portal inflammation, bile duct abnormalities, or both are present

  • Stage 2 (periportal stage): Periportal fibrosis is present, with or without periportal inflammation or prominent enlargement of the portal tracts with seemingly intact, newly formed limiting plates

  • Stage 3 (septal stage): Septal fibrosis with active inflammatory, passive paucicellular septa, or both are present

  • Stage 4 (cirrhosis): Nodules with various degrees of inflammation are present

See Workup for more detail.


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