How does the type and dosage of oral contraceptives affect a women's risk of breast cancer?

Updated: Dec 26, 2019
  • Author: Graham A Colditz, MD, DrPH; Chief Editor: Chandandeep Nagi, MD  more...
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Answer

Answer

The specific oral contraceptive formulation might be important in determining cancer risk, but studies of this issue are difficult because study participants may not be able to remember specific formulations and may use a number of formulations over time; very large studies are needed for enough statistical power to examine individual brands, and no satisfactory classification system exists to categorize specific oral contraceptive formulations by their effect on breast tissue. Although few studies have evaluated this issue, overall, there is no consistent evidence of a differential effect according to type or dose of either estrogen or progestin. [17] Data on specific formulations remain inconclusive.


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