What are the presentations of the non-pulmonary form of multiple organ dysfunction syndrome (MODS) in sepsis?

Updated: Jan 27, 2020
  • Author: Ali H Al-Khafaji, MD, MPH, FACP, FCCP, FCCM; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Answer

The second form of MODS presents quite differently. These patients often have an inciting source in organs other than the lungs—most commonly, intra-abdominal sepsis, extensive blood loss, pancreatitis, or vascular catastrophes. ALI or ARDS develops early, and dysfunction in other organ systems (hepatic, hematologic, cardiovascular, and renal) also develops much sooner than in the first form of MODS. Patients remain in a pattern of compensated dysfunction for several weeks, at which time they either recover or deteriorate further and die.


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