What are localizing symptoms of multiple organ dysfunction syndrome (MODS) in sepsis?

Updated: Jan 27, 2020
  • Author: Ali H Al-Khafaji, MD, MPH, FACP, FCCP, FCCM; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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The following localizing symptoms are some of the most useful clues to the etiology of both fever and sepsis:

  • Head and neck infections - Earache, sore throat, sinus pain, or swollen lymph glands

  • Chest and pulmonary infections - Cough (especially if productive), pleuritic chest pain, and dyspnea

  • Abdominal and gastrointestinal (GI) infections - Abdominal pain, nausea, vomiting, and diarrhea

  • Pelvic and genitourinary (GU) infections - Pelvic or flank pain, vaginal or urethral discharge, urea, frequency, urgency

  • Bone and soft tissue infections - Focal pain or tenderness, focal erythema, edema

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