What is the indication for broad-spectrum antibiotics in the treatment of systemic inflammatory response syndrome (SIRS)?

Updated: May 07, 2018
  • Author: Lewis J Kaplan, MD, FACS, FCCM, FCCP; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Because of increasing bacterial resistance, when an infectious cause for SIRS is a concern but no specific infection has been diagnosed, broad-spectrum antibiotics should be administered. Therapy for methicillin-resistant Staphylococcus aureus (MRSA) should be considered, owing to the rising prevalence of MRSA in the community.

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