What is the role of lab testing in the evaluation for systemic inflammatory response syndrome (SIRS)?

Updated: May 07, 2018
  • Author: Lewis J Kaplan, MD, FACS, FCCM, FCCP; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Answer

At minimum, a complete evaluation for systemic inflammatory response syndrome (SIRS) requires a complete blood cell (CBC) count with differential, to evaluate for leukocytosis or leukopenia. A white blood cell count of greater than 12,000/µL or less than 4,000/µL or with greater than 10% immature (band) forms on the differential is a criterion for SIRS. An increased percentage of bands is associated with an increased incidence of infectious causes of SIRS. [15]


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