What are the guidelines for treating influenza A and H5N1 infection in sepsis/septic shock?

Updated: Oct 07, 2020
  • Author: Andre Kalil, MD, MPH; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Answer

Other IDSA/ATS recommendations include the following [2] :

  • Influenza A – Early treatment (≤48 hr after symptoms onset) with oseltamivir or zanamivir; although these 2 agents are not recommended for use in uncomplicated influenza with symptoms longer than 48 hours, they may be used for reduction of viral shedding in inpatients or for influenza pneumonia

  • H5N1 infection – In suspected cases, administer oseltamivir and antibacterial agents against S pneumoniae and S aureus, which can cause secondary bacterial pneumonia in influenza patients


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