How is dopamine used for vasopressor therapy in sepsis/septic shock?

Updated: Oct 07, 2020
  • Author: Andre Kalil, MD, MPH; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Answer

Dopamine should be used only in certain highly specific situations, such as when there is a low risk of tachyarrhythmias and in the presence of coexistent bradycardia. Treatment usually begins at 5-10 µg/kg/min IV, and the infusion is adjusted according to the blood pressure and other hemodynamic parameters. Often, patients may require high dosages of dopamine (up to 20 µg/kg/min). Low-dose dopamine is not recommended for renal protection. [11, 60]


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