What is septic shock and what are the goals of hemodynamic therapy?

Updated: Oct 07, 2020
  • Author: Andre Kalil, MD, MPH; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Shock refers to a state of inability to maintain adequate tissue perfusion and oxygenation, which ultimately causes cellular, and then organ system, dysfunction. Therefore, the goals of hemodynamic therapy are restoration and maintenance of adequate tissue perfusion so as to prevent multiple organ dysfunction.

Careful clinical and invasive monitoring is required for assessment of global and regional perfusion. Shock at the bedside is defined by an MAP lower than 60 mm Hg or a decrease in MAP of 40 mm Hg from baseline.

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