When are routine culture and susceptibility studies indicated in the workup of sepsis/septic shock?

Updated: Oct 07, 2020
  • Author: Andre Kalil, MD, MPH; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Routine culture and susceptibility studies should be obtained in the following cases [2] :

  • Perforated appendicitis and other community-acquired intra-abdominal infections in which there is significant resistance of a common community isolate to an antimicrobial regimen in widespread use locally

  • Higher-risk patients who have a greater risk of harboring resistant pathogens, such as those with previous antibiotic exposure

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