What is the incidence of acute kidney injury (AKI) in sepsis/septic shock?

Updated: Oct 07, 2020
  • Author: Andre Kalil, MD, MPH; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Answer

Sepsis is the most common cause of AKI (ARF), which affects 40-70% of all critically ill patients, depending on how AKI is defined (eg, according to the RIFLE [risk, injury, failure, loss, and end stage] or AKIN [Acute Kidney Injury Network] classifications]). [43] AKI complicates therapy and worsens the overall outcome. [53] There is an increased risk of mortality when urosepsis is present with sepsis and septic shock [54] ; however, the global prognosis for patients with urosepsis is better than that for those with sepsis from other infectious sites.


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