What are the long-term effects of sepsis/septic shock?

Updated: Oct 07, 2020
  • Author: Andre Kalil, MD, MPH; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Although mortality is known to be high, the effect of sepsis on survivors’ quality of life of survivors has not been well characterized until comparatively recently. It is increasingly evident that septic shock is often a major sentinel event that has lasting effects on the patient’s independence, reliance on family support, and need for long-term nursing home or institutionalized care. [52]

Prolonged tissue hypoperfusion can lead to long-term neurologic and cognitive sequelae. [14] Newer evidence shows that septic shock in elderly persons leads to significant long-term cognitive and functional disability in comparison with hospitalized individuals who have nonsepsis conditions.

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