Why is bark scorpion antivenom for scorpion envenomation no longer produced?

Updated: Nov 09, 2018
  • Author: David Cheng, MD; Chief Editor: Joe Alcock, MD, MS  more...
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Answer

Until mid 2000, the antivenom for stings by the bark scorpion was manufactured in the Antivenin Production Laboratory of Arizona State University. Its use was controversial. It had been shown to produce rapid resolution of systemic symptoms but not to affect pain or paresthesias. Subsequently, many physicians recommended it in grade III and grade IV envenomations. Adverse effects included immediate and delayed hypersensitivity reactions. Initially, these reactions were rare, but they increased in frequency. This leads some physicians to prefer supportive care only, as they felt that the treatment was potentially worse than the disease. As death was rare if existent, they felt supportive care would yield similar outcomes. Currently, it is no longer being produced.


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