How is allergy to antivenom determined prior to treatment of scorpion envenomation?

Updated: Nov 09, 2018
  • Author: David Cheng, MD; Chief Editor: Joe Alcock, MD, MS  more...
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Answer

Skin tests have been performed to test for allergic response with locally produced antivenins. First, dilute 0.1 mL of antivenin in a 1:10 ratio with isotonic sodium chloride solution. Second, administer 0.2 mL intradermally. A positive test result is if a wheal develops within 10 minutes. The skin test has a sensitivity of 96% and a specificity of 68%.


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