Which medications in the drug class Anticholinergics, Respiratory are used in the treatment of Respiratory Failure?

Updated: Apr 07, 2020
  • Author: Ata Murat Kaynar, MD; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Anticholinergics, Respiratory

Anticholinergics antagonize the action of acetylcholine with muscarinic receptor on bronchial smooth muscle.

Ipratropium bromide (Atrovent HFA)

Ipratropium bromide is an anticholinergic medication that appears to inhibit vagally mediated reflexes by antagonizing the action of acetylcholine, specifically with the muscarinic receptor on bronchial smooth muscle. Vagal tone can be significantly increased in COPD; therefore, this can have a profound effect. Ipratropium can be combined with a beta-agonist because it may require 20 minutes to begin having an effect.

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