What is the benefit of powdered atropine in the treatment of organophosphate (OP) toxicity?

Updated: Dec 31, 2020
  • Author: Kenneth D Katz, MD, FAAEM, ABMT; Chief Editor: Sage W Wiener, MD  more...
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Because large amounts of atropine may be required for patients with OP poisoning, reconstitution of powdered atropine is a viable option, especially in mass-casualty settings. [21] Rajpal et al demonstrated the clinical safety and efficacy of sublingual atropine to healthy volunteers. This may offer another route of administration for the OP-poisoned patient, especially in a mass-casualty scenario. [22]

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