How is organophosphate (OP) toxicity diagnosed?

Updated: Dec 31, 2020
  • Author: Kenneth D Katz, MD, FAAEM, ABMT; Chief Editor: Sage W Wiener, MD  more...
  • Print

Organophosphate (OP) toxicity is a clinical diagnosis. Confirmation of organophosphate poisoning is based on the measurement of cholinesterase activity; typically, these results are not readily available in a clinically relevant timeframe. Although red blood cell (RBC) and plasma (pseudo) cholinesterase (PChE) levels can both be used, RBC cholinesterase correlates better with central nervous system (CNS) acetylcholinesterase (AChE) and is, therefore, a more useful marker of organophosphate poisoning.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!