Which conditions with depressed levels of plasma (pseudo) cholinesterase should be considered in the differential diagnosis of organophosphate (OP) toxicity?

Updated: Sep 22, 2018
  • Author: Kenneth D Katz, MD, FAAEM, ABMT; Chief Editor: Sage W Wiener, MD  more...
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Answer

Falsely depressed levels of plasma cholinesterase are observed in the following cases:

  • Liver dysfunction
  • Low-protein conditions
  • Neoplasia
  • Hypersensitivity reactions
  • Use of certain drugs (eg, succinylcholine, codeine, morphine)
  • Pregnancy
  • Genetic deficiencies

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