Which conditions with depressed levels of red blood cell (RBC) cholinesterase should be considered in the differential diagnosis of organophosphate (OP) toxicity?

Updated: Sep 22, 2018
  • Author: Kenneth D Katz, MD, FAAEM, ABMT; Chief Editor: Sage W Wiener, MD  more...
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Answer

Although organophosphate toxicity results in decreased cholinesterase, falsely depressed levels of red blood cell cholinesterase can be found in the following cases:

  • Pernicious anemia
  • Hemoglobinopathies
  • Use of antimalarial drugs
  • Blood collection tubes containing oxalate

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