What are the clinical presentations of organophosphate (OP) toxicity in children and adults?

Updated: Dec 31, 2020
  • Author: Kenneth D Katz, MD, FAAEM, ABMT; Chief Editor: Sage W Wiener, MD  more...
  • Print

Clinical presentation may vary, depending on the specific agent, exposure route, and amount. Signs and symptoms are due to both muscarinic and nicotinic effects.

Interestingly, a review of 31 children with organophosphate (OP) poisoning described that, in contrast to adults, the most common presentations were seizure and coma with relatively less muscarinic or nicotinic findings. [10] The authors hypothesized that the difference may be due to difficulty in detecting muscarinic findings in infants (eg, crying) and ingestion of contaminated produce instead of direct exposure to organophosphates.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!