What key updates were made to the revised American Heart Association (AHA) Guidelines for Prevention of Infective Endocarditis?

Updated: Feb 05, 2018
  • Author: Mary L Windle, PharmD; Chief Editor: Karlheinz Peter, MD, PhD  more...
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Answer

Answer

Major changes in the updated AHA guidelines include:

  • Only an extremely small number of cases of infective endocarditis (IE) might be prevented by antibiotic prophylaxis for dental procedures even if such prophylactic therapy were 100% effective
  • IE prophylaxis for dental procedures should be recommended only for patients with underlying cardiac conditions associated with the highest risk of adverse outcome from IE
  • For patients with these underlying cardiac conditions, prophylaxis is recommended for all dental procedures that involve manipulation of gingival tissue or the periapical region of teeth or perforation of the oral mucosa
  • Prophylaxis is not recommended based solely on an increased lifetime risk of acquisition of infective endocarditis
  • Administration of antibiotics solely to prevent endocarditis is not recommended for patients who undergo a genitourinary or gastrointestinal tract procedure

The antibiotic prophylactic regimens recommended by the AHA are only for patients with underlying cardiac conditions associated with the highest risk of adverse outcome from infective endocarditis. [1]


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