What is the role of HER2 testing in the pathologic assessment of breast tumors?

Updated: Mar 20, 2019
  • Author: Oudai Hassan, MD; Chief Editor: Chandandeep Nagi, MD  more...
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Human epidermal growth factor receptor 2 (HER2) expression and/or amplification should be evaluated in every primary invasive breast cancer either at the time of diagnosis or at the time of recurrence, principally to guide selection of trastuzumab in the adjuvant and/or metastatic setting. Other uses for HER2 evaluation are also discussed separately in Table 1 in the Overview section. [1]

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