How are mitotic counts assessed in breast cancer tumor grading?

Updated: Mar 20, 2019
  • Author: Oudai Hassan, MD; Chief Editor: Chandandeep Nagi, MD  more...
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Answer

Answer

The size of the high-power field (HPF) (40×) needs to be taken into account when assessing mitotic counts. Mitotic counts should be assessed at the periphery of the tumor, in the most mitotically active area. One should first look around at low power to look for mitotic figures. Only definite mitotic figures should be counted.


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