Which medications are administered in the treatment of heat stroke?

Updated: Nov 06, 2018
  • Author: Robert S Helman, MD; Chief Editor: Joe Alcock, MD, MS  more...
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Answer

In patients with heat stroke, benzodiazepines play a major role in providing sedation, controlling convulsions, and controlling shivering. Barbiturates (eg, phenobarbital) may be used to control convulsions if benzodiazepines are not effective.

Hypotension is treated first with cooling and intravenous crystalloid fluids; vasopressors may be needed for hypotension refractory to fluid repletion. Treatment of rhabdomyolysis involves infusing large amounts of intravenous fluids (as much as 10 L may be required), alkalinization of urine, and mannitol infusion.


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