What is the role of increased muscular activity in the etiology of heat stroke?

Updated: Aug 02, 2019
  • Author: Robert S Helman, MD; Chief Editor: Joe Alcock, MD, MS  more...
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Increased muscular activity may involve any of the following:

  • Exercise

  • Convulsions

  • Strychnine poisoning

  • Sympathomimetics

  • Drug withdrawal

  • Thyroid storm

Moderate physical exercise, convulsions, and shivering can double heat production and result in temperature elevations that generally are self-limited and resolve with discontinuation of the activity.

Strenuous exercise and status epilepticus can increase heat production 10-fold and, when uninterrupted, can overwhelm the body's heat-dissipating mechanisms, leading to dangerous rises in body temperature.

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