What is the role of single dose phenobarbital in the treatment of delirium tremens (DTs)?

Updated: Nov 06, 2020
  • Author: Michael James Burns, MD, FACEP, FACP, FIDSA; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Answer

A single dose of intravenous phenobarbital given in the emergency department may decrease the subsequent ICU admission rate and decrease the total dose of benzodiazepine and decrease the use of continuous lorazepam infusions required during the hospital course, without any increased adverse effects. [23]


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