Which medications should be considered following inpatient treatment of delirium tremens (DTs)?

Updated: Nov 06, 2020
  • Author: Michael James Burns, MD, FACEP, FACP, FIDSA; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
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Answer

Pharmacologic aids to alcohol cessation should be considered, because they may prevent relapse in patients who have been treated for alcohol dependence. Use of these agents for the long-term treatment of alcohol dependence can be initiated after detoxification to alcohol has been completed. FDA-approved medications used for the treatment of alcoholism include disulfiram, acamprosate, and 2 forms of naltrexone (oral and extended-release injectable). Topiramate, SSRIs, baclofen, and odansetron may also be effective but are not FDA approved. All these agents are, at-best, only modestly effective in the short term. [16]


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