Which medications in the drug class Antidiabetics, Biguanides are used in the treatment of Metabolic Syndrome?

Updated: Mar 30, 2020
  • Author: Stanley S Wang, JD, MD, MPH; Chief Editor: Yasmine S Ali, MD, MSCI, FACC, FACP  more...
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Antidiabetics, Biguanides

These agents reduce blood glucose levels.

Metformin (Glucophage, Fortamet, Glumetza, Riomet)

Metformin reduces hepatic glucose output, decreases intestinal absorption of glucose, and increases glucose uptake in the peripheral tissues (muscle and adipocytes). It is a major drug for use in patients who are obese and have type 2 diabetes. Metformin enhances weight reduction and improves lipid profile and vascular integrity. Individualize treatment with monotherapy or in combination with insulin or sulfonylureas.

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