Which medications in the drug class Lipid-Lowering Agents, Statins are used in the treatment of Metabolic Syndrome?

Updated: Oct 17, 2019
  • Author: Stanley S Wang, JD, MD, MPH; Chief Editor: Yasmine S Ali, MD, FACC, FACP, MSCI  more...
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Answer

Lipid-Lowering Agents, Statins

Management of elevated LDL-C includes consideration of all statins (3-hydroxy-3-methylglutaryl coenzyme A [HMG-CoA] reductase inhibitors) at all indicated ranges, as there are several formulations available with different doses and potencies. Statins affect the lipid profile favorably and provide possible pleiotropic benefits. The choice of drug and dose should be based on guidelines but individualized to the patient.

Atorvastatin (Lipitor)

Atorvastatin is an HMG-CoA reductase inhibitor that inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase.

Rosuvastatin (Crestor)

Rosuvastatin is an HMG-CoA reductase inhibitor that inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase.

Fluvastatin (Lescol, Lescol XL)

Fluvastatin is an HMG-CoA reductase inhibitor that inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase.

Lovastatin (Altoprev, Mevacor)

Lovastatin is an HMG-CoA reductase inhibitor that inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase.

Simvastatin (Zocor)

Pravastatin (Pravachol)

Pitavastatin (Livalo)


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