What is the role of CPAP therapy in the treatment of metabolic syndrome?

Updated: Mar 29, 2017
  • Author: Stanley S Wang, JD, MD, MPH; Chief Editor: Yasmine S Ali, MD, FACC, FACP, MSCI  more...
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Answer

Treatment of associated obstructive sleep apnea may play a significant role in the management of metabolic syndrome. [87] In a 2011 study, patients with at least moderate obstructive sleep apnea who used continuous positive airway pressure (CPAP) therapy for 3 months showed significant improvements in their metabolic profile, including reductions in systolic and diastolic blood pressure, LDL-C, triglycerides, and glycated hemoglobin. Furthermore, reversal of metabolic syndrome occurred to a greater degree in the CPAP therapy group than in patients who underwent sham treatment (13% vs 1%, respectively). [88]


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