What are the NHLBI and AHA diagnostic criteria for metabolic syndrome?

Updated: Mar 29, 2017
  • Author: Stanley S Wang, JD, MD, MPH; Chief Editor: Yasmine S Ali, MD, FACC, FACP, MSCI  more...
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Answer

According to guidelines from the National Heart, Lung, and Blood Institute (NHLBI) and the American Heart Association (AHA), metabolic syndrome is diagnosed when a patient has at least 3 of the following 5 conditions:

  • Fasting glucose ≥100 mg/dL (or receiving drug therapy for hyperglycemia)

  • Blood pressure ≥130/85 mm Hg (or receiving drug therapy for hypertension)

  • Triglycerides ≥150 mg/dL (or receiving drug therapy for hypertriglyceridemia)

  • HDL-C < 40 mg/dL in men or < 50 mg/dL in women (or receiving drug therapy for reduced HDL-C)

  • Waist circumference ≥102 cm (40 in) in men or ≥88 cm (35 in) in women; if Asian American, ≥90 cm (35 in) in men or ≥80 cm (32 in) in women

To address variation between professional guidelines, the NHLBI, AHA, International Diabetes Foundation (IDF), and others have proposed a harmonized definition of metabolic syndrome. [1]


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