How is myeloid sarcoma defined?

Updated: Jul 28, 2020
  • Author: Amandeep Aneja, MD; Chief Editor: Aliyah R Sohani, MD  more...
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Myeloid sarcoma is an extramedullary tumor mass consisting of myeloid blasts that efface the tissue architecture. [8]  The latter feature is particularly important to distinguish myeloid sarcoma from tissue infiltration by leukemic blasts in acute myeloid leukemia (AML) patients; AML tissue infiltrates do not form tumoral masses that efface the underlying architecture.

Associated disorders include granulocytic sarcoma (ie, chloroma), monoblastic/monocytic sarcoma, and erythroid sarcoma. [8]

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