How should syncope be evaluated in suspected Brugada syndrome (BrS)?

Updated: Apr 03, 2020
  • Author: Jose M Dizon, MD; Chief Editor: Mikhael F El-Chami, MD  more...
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Many patients with Brugada syndrome are young and otherwise healthy and may present with syncope. Patients with syncope should not be assumed to have a benign condition, and a 12-lead ECG should be performed.

A drug challenge with a sodium channel blocker should be considered in patients with syncope in whom no obvious cause is found. An experienced physician should interpret the ECGs, and an electrophysiologist should review them if possible.

Further testing may be indicated to exclude other diagnostic possibilities.

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