What is the role of genetics in the etiology of Brugada syndrome (BrS)?

Updated: Apr 03, 2020
  • Author: Jose M Dizon, MD; Chief Editor: Mikhael F El-Chami, MD  more...
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Answer

Brugada syndrome is genetically determined and has an autosomal dominant pattern of transmission in about 50% of familial cases (see Etiology). The typical patient with Brugada syndrome is young, male, and otherwise healthy, with normal general medical and cardiovascular physical examinations.


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