How is dopamine used in the treatment of heart failure?

Updated: May 07, 2018
  • Author: Ioana Dumitru, MD; Chief Editor: Gyanendra K Sharma, MD, FACC, FASE  more...
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Answer

Low-dose dopamine has been used in combination with diuretic therapy, on the supposition that it can increase kidney perfusion. Data have been contradictory, however. In a randomized controlled study, Giamouzis et al found that the combination of low-dose furosemide and low-dose dopamine was equally as effective as high-dose furosemide for kidney function in patients with acute decompensated heart failure. [110]  In addition, patients who received dopamine and furosemide were less likely to have worsened renal function or hypokalemia at 24 hours. [110]


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