How does a finding of sarcomatoid change affect the prognosis of renal cell carcinoma (RCC)?

Updated: Jul 02, 2019
  • Author: YiFen Zhang, MD, PhD; Chief Editor: Liang Cheng, MD  more...
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Answer

Answer

Sarcomatoid change in renal cell carcinoma (RCC) is not very rare, and it is associated with aggressive tumor growth and the development of metastasis; therefore, this change is associated with a worse prognosis. Sarcomatoid change can be seen in ccRCC, pRCC, and chromophobe RCC and should be included in the pathologic report.


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