Which microscopic findings are characteristic of Fuhrman system grade 4 renal cell carcinoma (RCC)?

Updated: Jul 02, 2019
  • Author: YiFen Zhang, MD, PhD; Chief Editor: Liang Cheng, MD  more...
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Answer

Answer

The nuclei are pleomorphic with open chromatin or hyperchromatic and single or multiple macronucleoli, as depicted in the following image.

Pathology grading of renal cell carcinoma. Renal c Pathology grading of renal cell carcinoma. Renal cell carcinoma, clear cell type, Fuhrman grade 4/4.

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