Which microscopic pathologic findings are characteristic of basaloid squamous cell carcinoma of the urinary bladder?

Updated: Jun 11, 2019
  • Author: Muhammad T Idrees, MD; Chief Editor: Liang Cheng, MD  more...
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Answer

Answer

Only a few cases of basaloid squamous cell carcinoma of the bladder has been reported, [39, 40] including that of a 60-year-old woman with incontinence, intractable urinary tract infections, and flat, cystoscopic lesions. [41] Microscopically, the tumor was composed of nests of basaloid cells with numerous mitoses, areas of squamous differentiation, and squamous cell carcinoma in situ. Bostwick and Cheng have proposed that the correct terminology should be urothelial carcinoma with basaloid features rather than basaloid squamous cell carcinoma. [42]


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