Which gross findings are characteristic of translocation-associated renal cell carcinomas (RCCs)?

Updated: May 17, 2017
  • Author: Angela J Wu, MD; Chief Editor: Liang Cheng, MD  more...
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Translocation-associated renal cell carcinoma (RCC) usually grossly resembles a conventional clear cell RCC; lesions are typically cortical or subcapsular, well circumscribed, and tan-yellow, with variegated, focally necrotic, and hemorrhagic cut surfaces. (See the image below.) [1, 2, 3, 12]

Xp11.2 translocation-associated renal cell carcino Xp11.2 translocation-associated renal cell carcinomas are generally cortical or subcapsular, well-circumscribed lesions with yellow-tan, variegated cut surfaces. Image courtesy of University of Michigan.

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