What is the prognosis for stromal tumors of uncertain malignant potential (STUMP)?

Updated: Jan 04, 2021
  • Author: Fabio R Tavora, MD, PhD; Chief Editor: Liang Cheng, MD  more...
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Answer

Answer

Patients with stromal tumors of uncertain malignant potential (STUMP) have a good prognosis, and most cases of STUMP do not seem to behave aggressively. In fact, it has been argued that they represent benign stromal hyperplasia with reactive atypia similar to stromal changes seen in other sites, such as the cervix, vagina, vulva, bladder, and breast. [26, 9] However, Herawi et al reported that 16% (7/43) of STUMPs progressed to or were subsequently found to be associated with prostatic stromal sarcomas. [12]


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