How does radiation therapy for prostate cancer affect the patient's quality of life?

Updated: Dec 30, 2020
  • Author: Kenneth A Iczkowski, MD; Chief Editor: Liang Cheng, MD  more...
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About 50% of men undergoing high-dose-rate brachytherapy followed by external beam radiotherapy reported a significant decrease in Expanded Prostate Cancer Index Composite (EPIC) urinary, bowel, sexual, and hormonal domain scores by 12 months. In comparison, those undergoing a dose of radiation directed at the urethra had a greater deterioration in quality of life. [32, 33]  Radiotherapy seems to be the treatment of choice for Gleason score 7 prostate cancer patients; this modality has been associated with superior disease-free survival at 5 years compared to RP alone [34]  


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