What is the prognosis of prostatic lymphoma/leukemia?

Updated: Dec 22, 2019
  • Author: Joshua I Warrick, MD; Chief Editor: Liang Cheng, MD  more...
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Answer

Answer

As in other locations, prognosis in prostatic involvement by leukemia/lymphoma is dependent on the subtype.

The majority of cases are low grade, predominantly chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). As such, the prognosis in these cases is generally favorable. In a large consecutive series with follow-up data, which showed predominantly low-grade leukemia/lymphoma, only one patient had died from disease at follow-up. [1]

In contrast, diffuse large B-cell lymphoma (DLBCL), which is often primary, carries a considerably less favorable prognosis. In a large series of primary prostatic lymphomas to date, which notably included numerous high-grade secondary prostatic lymphomas in survival analysis, 5-year lymphoma-specific survival was only 33%. [9]


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